Testmiljö
Observera att detta är en testmiljö för utveckling som inte ska användas som underlag för klinisk bedömning. Besök Janusmed här: https://janusmed.se

6/13/2026

Janusmed fosterpåverkan

Janusmed fosterpåverkan – Somadril comp.

Janusmed fosterpåverkan tillhandahåller bedömningar av eventuella risker för fostret, när en gravid kvinna använder olika läkemedel. Observera att texterna är generella, och att en bedömning måste göras i varje enskilt fall. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

För att komma till startsidan för Janusmed fosterpåverkan och för att göra sökningar klicka här.

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Karisoprodol Testmiljö

Karisoprodol

Klass : 2

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Skriv ut

Kontakta oss

  1. Reprotox. Carisoprodol. Micromedex [www]. [cited 2024-12-09].

  2. Briggs G, Towers CV, Forinash AB. Drugs in pregnancy and lactation: A reference guide to fetal and neonatal risk. 12th ed; 2021.

  3. EMA. Vetenskapliga slutsatser och skäl för tillfällig indragning av godkännande för försäljning framlagda av EMEA. EMA [www]. [cited 2024-12-09].

  4. Birgitta Bülow, Bo Bergman. Somadril och Somadril comp avregistreras den 1 juni 2008. Läkartidningen. 2008 3 14;0(14):0.

  1. Reprotox. Carisoprodol. Micromedex [www]. [cited 2024-12-09].
  2. Briggs G, Towers CV, Forinash AB. Drugs in pregnancy and lactation: A reference guide to fetal and neonatal risk. 12th ed; 2021.
  3. EMA. Vetenskapliga slutsatser och skäl för tillfällig indragning av godkännande för försäljning framlagda av EMEA. EMA [www]. [cited 2024-12-09].
  4. Birgitta Bülow, Bo Bergman. Somadril och Somadril comp avregistreras den 1 juni 2008. Läkartidningen. 2008 3 14;0(14):0.
2 2
2 2

Koffein Testmiljö

Koffein

Klass : 2

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Skriv ut

Kontakta oss

  1. Chen LW, Wu Y, Neelakantan N, Chong MF, Pan A, van Dam RM. Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies. Public Health Nutr. 2016;19:1233-44.

  2. Wisborg K, Kesmodel U, Bech BH et al. Maternal consumption of coffee during pregnancy and stillbirth and infant death in first year of life: prospective study. BMJ 2003;326:420-2.

  3. Cnattingius S, Signorello LB, Annerén G, Clausson B, Ekbom A, Ljunger E et al. Caffeine intake and the risk of first-trimester spontaneous abortion. New Engl J Med 2000;343:1839-45.

  4. Christian MS, Brent RL. Teratogen update: Evaluation of the reproductive and developmental risks of caffeine. Teratology 2001;64:51-78.

  5. Grosso LM, Rosenberg KD, Belanger K, Saftlas AF, Leaderer B, Bracken MB. Maternal caffeine intake and intrauterine growth retardation. Epidemiology 2001;12:447-55.

  6. Sengpiel V, Elind E, Bacelis J, Nilsson S, Grove J, Myhre R et al. Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med. 2013;11(0):42.

  7. Wikoff D, Welsh BT, Henderson R, Brorby GP, Britt J, Myers E et al. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol. 2017;109(0):585-648.

  8. Koffein – råd till gravida och ammande 2019. Livsmedelsverket [www]. [cited 2020-03-10].

  1. Chen LW, Wu Y, Neelakantan N, Chong MF, Pan A, van Dam RM. Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies. Public Health Nutr. 2016;19:1233-44.
  2. Wisborg K, Kesmodel U, Bech BH et al. Maternal consumption of coffee during pregnancy and stillbirth and infant death in first year of life: prospective study. BMJ 2003;326:420-2.
  3. Cnattingius S, Signorello LB, Annerén G, Clausson B, Ekbom A, Ljunger E et al. Caffeine intake and the risk of first-trimester spontaneous abortion. New Engl J Med 2000;343:1839-45.
  4. Christian MS, Brent RL. Teratogen update: Evaluation of the reproductive and developmental risks of caffeine. Teratology 2001;64:51-78.
  5. Grosso LM, Rosenberg KD, Belanger K, Saftlas AF, Leaderer B, Bracken MB. Maternal caffeine intake and intrauterine growth retardation. Epidemiology 2001;12:447-55.
  6. Sengpiel V, Elind E, Bacelis J, Nilsson S, Grove J, Myhre R et al. Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med. 2013;11(0):42.
  7. Wikoff D, Welsh BT, Henderson R, Brorby GP, Britt J, Myers E et al. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol. 2017;109(0):585-648.
  8. Koffein – råd till gravida och ammande 2019. Livsmedelsverket [www]. [cited 2020-03-10].
1 1
1 1

Paracetamol Testmiljö

Paracetamol

Klass : 1

Visa all info

Skriv ut

Kontakta oss

  1. UK Teratology Information Service (UKTIS). Therapeutic use of paracetamol in pregnancy August 2023 Version 2. UKTIS [www]. [cited 2024-05-02].

  2. Bauer AZ, Swan SH, Kriebel D, Liew Z, Taylor HS, Bornehag CG, Andrade AM, Olsen J, Jensen RH, Mitchell RT, Skakkebaek NE, Jégou B, Kristensen DM. Paracetamol use during pregnancy - a call for precautionary action. Nat Rev Endocrinol. 2021;12:757-766.

  3. Ricci, C, Albanese, CM, Pablo, LA, et al. In utero acetaminophen exposure and child neurodevelopmental outcomes: Systematic review and meta-analysis. Paediatr Perinat Epidemiol. 2023; 00: 1- 12. doi:10.1111/ppe.12963

  4. Ystrom E, Gustavson K, Brandlistuen RE, Knudsen GP, Magnus P, Susser E et al. Prenatal Exposure to Acetaminophen and Risk of ADHD. Pediatrics. 2017;140:.

  5. Liew Z, Ritz B, Rebordosa C, Lee PC, Olsen J. Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. JAMA Pediatr. 2014;168:313-20.

  6. Brandlistuen RE, Ystrom E, Nulman I, Koren G, Nordeng H. Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study. Int J Epidemiol. 2013;42:1702-13.

  7. Damkier P, Gram EB, Ceulemans M, Panchaud A, Cleary B, Chambers C et al. Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstet Gynecol. 2025;145(2):168-176.

  8. Damkier P, Cleary B, Weber-Schoendorfer C, Shechtman S, Cassina M, Panchaud A et al. Handle with care - interpretation, synthesis and dissemination of data on paracetamol in pregnancy. Nat Rev Endocrinol. 2021.

  9. Ahlqvist VH, Sjöqvist H, Dalman C, Karlsson H, Stephansson O, Johansson S et al. Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205-1214.

  10. Prahm KP, Chen P, Rode L, Ekelund CK, Husby KR, Bergholt T, Lidegaard Ø, Scheller NM, Mikkelsen AP. Acetaminophen Exposure During Pregnancy and the Risk of Autism in Offspring. JAMA Pediatr. 2026 Apr 13:e260646. doi: 10.1001/jamapediatrics.2026.0646. Epub ahead of print.

  11. Gustavson, K., Ystrom, E., Ask, H., Ask Torvik, F., Hornig, M., Susser, E., Lipkin, W.I., Lupattelli, A., Stoltenberg, C., Magnus, P., Mjaaland, S., Askeland, R.B., Walle, K.M., Bresnahan, M., Nordeng, H. and Reichborn-Kjennerud, T. (2021), Acetaminophen use during pregnancy and offspring attention deficit hyperactivity disorder – a longitudinal sibling control study. JCPP Advances, 1: e12020. https://doi.org/10.1002/jcv2.12020

  12. Okubo Y, Hayakawa I, Sugitate R, Nariai H. Maternal Acetaminophen Use and Offspring's Neurodevelopmental Outcome: A Nationwide Birth Cohort Study. Paediatr Perinat Epidemiol. 2025 Sep 2. doi: 10.1111/ppe.70071. Epub ahead of print.

  13. D'Antonio, Francesco et al. Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis. The Lancet Obstetrics, Gynaecology, & Women’s Health. 2026 Jan 16; doi: 10.1016/S3050-5038(25)00211-0. Online first

  14. Fan G, Wang B, Liu C, Li D. Prenatal paracetamol use and asthma in childhood: A systematic review and meta-analysis. Allergol Immunopathol (Madr). 2017;45(6):528-533.

  15. Shaheen SO, Lundholm C, Brew BK, Almqvist C. Prescribed analgesics in pregnancy and risk of childhood asthma. Eur Respir J. 2019;53(5).

  16. Källén B, Finnström O, Nygren KG, Otterblad Olausson P. Maternal drug use during pregnancy and asthma risk among children. Pediatr Allergy Immunol. 2013;24:28-32.

  17. UK Teratology Information Service (UKTIS). Paracetamol overdose in pregnancy August, 2023 Version 14. UKTIS [www]. [cited 2024-05-02].

  18. McElhatton PR, Sullivan FM, Volans GN. Paracetamol overdose in pregnancy analysis of the outcomes of 300 cases referred to the Teratology Information Service. Reprod Toxicol. 1997;11:85-94.

  1. UK Teratology Information Service (UKTIS). Therapeutic use of paracetamol in pregnancy August 2023 Version 2. UKTIS [www]. [cited 2024-05-02].
  2. Bauer AZ, Swan SH, Kriebel D, Liew Z, Taylor HS, Bornehag CG, Andrade AM, Olsen J, Jensen RH, Mitchell RT, Skakkebaek NE, Jégou B, Kristensen DM. Paracetamol use during pregnancy - a call for precautionary action. Nat Rev Endocrinol. 2021;12:757-766.
  3. Ricci, C, Albanese, CM, Pablo, LA, et al. In utero acetaminophen exposure and child neurodevelopmental outcomes: Systematic review and meta-analysis. Paediatr Perinat Epidemiol. 2023; 00: 1- 12. doi:10.1111/ppe.12963
  4. Ystrom E, Gustavson K, Brandlistuen RE, Knudsen GP, Magnus P, Susser E et al. Prenatal Exposure to Acetaminophen and Risk of ADHD. Pediatrics. 2017;140:.
  5. Liew Z, Ritz B, Rebordosa C, Lee PC, Olsen J. Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. JAMA Pediatr. 2014;168:313-20.
  6. Brandlistuen RE, Ystrom E, Nulman I, Koren G, Nordeng H. Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study. Int J Epidemiol. 2013;42:1702-13.
  7. Damkier P, Gram EB, Ceulemans M, Panchaud A, Cleary B, Chambers C et al. Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstet Gynecol. 2025;145(2):168-176.
  8. Damkier P, Cleary B, Weber-Schoendorfer C, Shechtman S, Cassina M, Panchaud A et al. Handle with care - interpretation, synthesis and dissemination of data on paracetamol in pregnancy. Nat Rev Endocrinol. 2021.
  9. Ahlqvist VH, Sjöqvist H, Dalman C, Karlsson H, Stephansson O, Johansson S et al. Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205-1214.
  10. Prahm KP, Chen P, Rode L, Ekelund CK, Husby KR, Bergholt T, Lidegaard Ø, Scheller NM, Mikkelsen AP. Acetaminophen Exposure During Pregnancy and the Risk of Autism in Offspring. JAMA Pediatr. 2026 Apr 13:e260646. doi: 10.1001/jamapediatrics.2026.0646. Epub ahead of print.
  11. Gustavson, K., Ystrom, E., Ask, H., Ask Torvik, F., Hornig, M., Susser, E., Lipkin, W.I., Lupattelli, A., Stoltenberg, C., Magnus, P., Mjaaland, S., Askeland, R.B., Walle, K.M., Bresnahan, M., Nordeng, H. and Reichborn-Kjennerud, T. (2021), Acetaminophen use during pregnancy and offspring attention deficit hyperactivity disorder – a longitudinal sibling control study. JCPP Advances, 1: e12020. https://doi.org/10.1002/jcv2.12020
  12. Okubo Y, Hayakawa I, Sugitate R, Nariai H. Maternal Acetaminophen Use and Offspring's Neurodevelopmental Outcome: A Nationwide Birth Cohort Study. Paediatr Perinat Epidemiol. 2025 Sep 2. doi: 10.1111/ppe.70071. Epub ahead of print.
  13. D'Antonio, Francesco et al. Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis. The Lancet Obstetrics, Gynaecology, & Women’s Health. 2026 Jan 16; doi: 10.1016/S3050-5038(25)00211-0. Online first
  14. Fan G, Wang B, Liu C, Li D. Prenatal paracetamol use and asthma in childhood: A systematic review and meta-analysis. Allergol Immunopathol (Madr). 2017;45(6):528-533.
  15. Shaheen SO, Lundholm C, Brew BK, Almqvist C. Prescribed analgesics in pregnancy and risk of childhood asthma. Eur Respir J. 2019;53(5).
  16. Källén B, Finnström O, Nygren KG, Otterblad Olausson P. Maternal drug use during pregnancy and asthma risk among children. Pediatr Allergy Immunol. 2013;24:28-32.
  17. UK Teratology Information Service (UKTIS). Paracetamol overdose in pregnancy August, 2023 Version 14. UKTIS [www]. [cited 2024-05-02].
  18. McElhatton PR, Sullivan FM, Volans GN. Paracetamol overdose in pregnancy analysis of the outcomes of 300 cases referred to the Teratology Information Service. Reprod Toxicol. 1997;11:85-94.