Testmiljö
Observera att detta är en testmiljö för utveckling som inte ska användas som underlag för klinisk bedömning. Besök Janusmed här: https://janusmed.se

3/29/2024

Janusmed fosterpåverkan

Janusmed fosterpåverkan – Acetylsalicylsyra APL

Janusmed fosterpåverkan tillhandahåller bedömningar av eventuella risker för fostret, när en gravid kvinna använder olika läkemedel. Observera att texterna är generella, och att en bedömning måste göras i varje enskilt fall. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

För att komma till startsidan för Janusmed fosterpåverkan och för att göra sökningar klicka här.

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Acetylsalicylsyra Testmiljö

Acetylsalicylsyra

Klass : 2

  1. Koren G, Florescu A, Costei AM, Boskovic R, Moretti ME. Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis. Ann Pharmacother. 2006;40:824-9.
  2. Norton ME. Teratogen update: fetal effects of indomethacin administration during pregnancy. Teratology. 1997;56:282-92.
  3. Souter D, Harding J, McCowan L, O´Donnell C, McLeay E, Baxendale H. Antenatal indomethacin - adverse fetal effects confirmed. Aust N Z J Obstet Gynaecol 1998;38:11-6.
  4. Dathe K, Hultzsch S, Pritchard LW, Schaefer C. Risk estimation of fetal adverse effects after short-term second trimester exposure to non-steroidal anti-inflammatory drugs: a literature review. Eur J Clin Pharmacol. 2019;75(10):1347-1353.
  5. Hernández-Díaz S, García-Rodríguez LA. Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs. Am J Med. 2001;110 Suppl 3A:20S-7S.
  6. Dathe K, Frank J, Padberg S, Hultzsch S, Beck E, Schaefer C. Fetal adverse effects following NSAID or metamizole exposure in the 2nd and 3rd trimester: an evaluation of the German Embryotox cohort. BMC Pregnancy Childbirth. 2022;22(1):666.
  7. Alano MA, Ngougmna E, Ostrea EM Jr, Konduri GG. Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn. Pediatrics 2001;107:519-23.
  8. Perkin RM, Levin DL, Clark R. Serum salicylate levels and right-to-left ductus shunts in newborn infants with persistent pulmonary hypertension. J Pediatr. 1980;96(4):721-6.
  9. Hendricks SK, Smith JR, Moore DE, Brown ZA. Oligohydramnios associated with prostaglandin synthetase inhibitors in preterm labour. Br J Obstet Gynaecol. 1990;97:312-6.
  10. Østensen M, Khamashta M, Lockshin M, Parke A, Brucato A, Carp H et al. Anti-inflammatory and immunosuppressive drugs and reproduction. Arthritis Res Ther. 2006;8:209.
  11. Stuart MJ, Gross SJ, Elrad H, Graeber JE. Effects of acetylsalicylic-acid ingestion on maternal and neonatal hemostasis. N Engl J Med. 1982;307(15):909-12.
  12. UKTIS. Use of aspirin and aspirin overdose in pregnancy. July 2019. UKTIS [www]. UKTIS. [cited 2023-04-17].
  13. Czeizel A E, Rockenbauer M, Mosonyi A. A population-based case-control teratologic study of acetylsalicylic acid treatments during pregnancy. Pharmacoepidemiol Drug Saf. 2000;9(3):193-205.
  14. Kozer E, Nikfar S, Costei A et al. Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis. Am J Obstet Gynecol 2002;187:1623-30.
  15. Werler MM, Sheehan JE, Mitchell AA. Maternal medication use and risks of gastroschisis and small intestinal atresia. Am J Epidemiol 2002;155:26-31.
  16. Abe K, Honein MA, Moore CA. Maternal febrile illness, medication use, and the risk of congenital renal anomalies. Birth Defets Research Part A 2003;67:911-8.
  17. Luteijn JM, Brown MJ, Dolk H. Influenza and congenital anomalies: a systematic review and meta-analysis. Hum Reprod. 2014;29(4):809-23.
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Acetylsalicylsyra – lågdos Testmiljö

Acetylsalicylsyra – lågdos

Klass : 2

  1. UKTIS. Use of aspirin and aspirin overdose in pregnancy. July 2019. UKTIS [www]. UKTIS. [cited 2023-04-17].
  2. Czeizel A E, Rockenbauer M, Mosonyi A. A population-based case-control teratologic study of acetylsalicylic acid treatments during pregnancy. Pharmacoepidemiol Drug Saf. 2000;9(3):193-205.
  3. Kozer E, Nikfar S, Costei A et al. Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis. Am J Obstet Gynecol 2002;187:1623-30.
  4. Werler MM, Sheehan JE, Mitchell AA. Maternal medication use and risks of gastroschisis and small intestinal atresia. Am J Epidemiol 2002;155:26-31.
  5. Abe K, Honein MA, Moore CA. Maternal febrile illness, medication use, and the risk of congenital renal anomalies. Birth Defets Research Part A 2003;67:911-8.
  6. Luteijn JM, Brown MJ, Dolk H. Influenza and congenital anomalies: a systematic review and meta-analysis. Hum Reprod. 2014;29(4):809-23.
  7. Garza-Galvan M E, Ferrigno A S, Campos-Zamora M, Bain P A, Rae Easter S, Kim J, Figueras F, Farber M K, Lumbreras-Marquez M I. Low-dose aspirin use in the first trimester of pregnancy and odds of congenital anomalies: A meta-analysis of randomized controlled trials. Int J Gynaecol Obstet. 2023;2(160):526-537.
  8. Duley L, Meher S, Hunter KE, Seidler AL, Askie LM. Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev. 2019;2019(10):CD004659.
  9. Choi YJ, Shin S. Aspirin Prophylaxis During Pregnancy: A Systematic Review and Meta-Analysis. Am J Prev Med. 2021;61(1):e31-e45.
  10. Landman AJEMC, van Limburg Stirum EVJ, de Boer MA, van 't Hooft J, Ket JCF, Leemhuis AG et al. Long-term health and neurodevelopment in children after antenatal exposure to low-dose aspirin for the prevention of preeclampsia and fetal growth restriction: A systematic review of randomized controlled trials. Eur J Obstet Gynecol Reprod Biol. 2021;267(0):213-220.
  11. Grab D, Paulus WE, Erdmann M, Terinde R, Oberhoffer R, Lang D et al. Effects of low-dose aspirin on uterine and fetal blood flow during pregnancy: results of a randomized, placebo-controlled, double-blind trial. Ultrasound Obstet Gynecol. 2000;15(1):19-27.
  12. James AH, Brancazio LR, Price T. Aspirin and reproductive outcomes. Obstet Gynecol Surv. 2008;63(1):49-57.
  13. Maher JE, Owen J, Hauth J, Goldenberg R, Parker CR, Copper RL. The effect of low-dose aspirin on fetal urine output and amniotic fluid volume. Am J Obstet Gynecol. 1993;169(4):885-8.