Testmiljö
Observera att detta är en testmiljö för utveckling som inte ska användas som underlag för klinisk bedömning. Besök Janusmed här: https://janusmed.se

11/21/2024

Janusmed fosterpåverkan

Janusmed fosterpåverkan – Nivolumab

Janusmed fosterpåverkan tillhandahåller bedömningar av eventuella risker för fostret, när en gravid kvinna använder olika läkemedel. Observera att texterna är generella, och att en bedömning måste göras i varje enskilt fall. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

För att komma till startsidan för Janusmed fosterpåverkan och för att göra sökningar klicka här.

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Nivolumab Testmiljö

Nivolumab

Klass : 3

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  1. Ngu SF, Ngan HY. Chemotherapy in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2016;33(0):86-101.

  2. Boere I, Lok C, Vandenbroucke T, Amant F. Cancer in pregnancy: safety and efficacy of systemic therapies. Curr Opin Oncol. 2017;29(5):328-334.

  3. Lambertini M, Peccatori FA, Azim HA. Targeted agents for cancer treatment during pregnancy. Cancer Treat Rev. 2015;41(4):301-9.

  4. Weber-Schoendorfer C, Chambers C, Wacker E, Beghin D, Bernard N, Network of French Pharmacovigilance Centers et al. Pregnancy outcome after methotrexate treatment for rheumatic disease prior to or during early pregnancy: a prospective multicenter cohort study. Arthritis Rheumatol. 2014;66(5):1101-10.

  5. United Kingdom Teratology Information Services (UKTIS). Methotrexate in pregnancy. 2016. Tillgänglig från: www.toxbase.com. Hämtad: 2018-06-15

  6. Arnon J, Meirow D, Lewis-Roness H, Ornoy A. Genetic and teratogenic effects of cancer treatments on gametes and embryos. Hum Reprod Update. 2001;7(4):394-403.

  7. Haggar FA, Pereira G, Preen D, Holman CD, Einarsdottir K. Adverse obstetric and perinatal outcomes following treatment of adolescent and young adult cancer: a population-based cohort study. PLoS One. 2014;9(12):e113292.

  8. Dohle GR. Male infertility in cancer patients: Review of the literature. Int J Urol. 2010;17(4):327-31.

  9. Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL et al. Potential seminal transport of pharmaceuticals to the conceptus. Reprod Toxicol. 2015;58(0):213-21.

  10. Klemmt L, Scialli AR. The transport of chemicals in semen. Birth Defects Res B Dev Reprod Toxicol. 2005;74(2):119-31.

  11. EMA. OPDIVO. Assessment report 2015-04-23. https://goo.gl/PxOSzv

  12. Poulet FM, Wolf JJ, Herzyk DJ, DeGeorge JJ. An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors. Birth Defects Res B Dev Reprod Toxicol. 2016;107(2):108-19.

  13. Xu W, Moor RJ, Walpole ET, Atkinson VG. Pregnancy with successful foetal and maternal outcome in a melanoma patient treated with nivolumab in the first trimester: case report and review of the literature. Melanoma Res. 2019;29(3):333-337.

  14. Menzer C, Beedgen B, Rom J, Duffert CM, Volckmar AL, Sedlaczek O et al. Immunotherapy with ipilimumab plus nivolumab in a stage IV melanoma patient during pregnancy. Eur J Cancer. 2018;104:239-242.

  15. Evens AM, Brandt JS, Peer CJ, Yin T, Schaar D, Farooq F et al. Checkpoint inhibitor immunotherapy during pregnancy for relapsed-refractory Hodgkin lymphoma. Am J Hematol. 2022;97(6):833-838.

  16. Simister NE. Placental transport of immunoglobulin G. Vaccine. 2003;21(24):3365-9.

  1. Ngu SF, Ngan HY. Chemotherapy in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2016;33(0):86-101.
  2. Boere I, Lok C, Vandenbroucke T, Amant F. Cancer in pregnancy: safety and efficacy of systemic therapies. Curr Opin Oncol. 2017;29(5):328-334.
  3. Lambertini M, Peccatori FA, Azim HA. Targeted agents for cancer treatment during pregnancy. Cancer Treat Rev. 2015;41(4):301-9.
  4. Weber-Schoendorfer C, Chambers C, Wacker E, Beghin D, Bernard N, Network of French Pharmacovigilance Centers et al. Pregnancy outcome after methotrexate treatment for rheumatic disease prior to or during early pregnancy: a prospective multicenter cohort study. Arthritis Rheumatol. 2014;66(5):1101-10.
  5. United Kingdom Teratology Information Services (UKTIS). Methotrexate in pregnancy. 2016. Tillgänglig från: www.toxbase.com. Hämtad: 2018-06-15
  6. Arnon J, Meirow D, Lewis-Roness H, Ornoy A. Genetic and teratogenic effects of cancer treatments on gametes and embryos. Hum Reprod Update. 2001;7(4):394-403.
  7. Haggar FA, Pereira G, Preen D, Holman CD, Einarsdottir K. Adverse obstetric and perinatal outcomes following treatment of adolescent and young adult cancer: a population-based cohort study. PLoS One. 2014;9(12):e113292.
  8. Dohle GR. Male infertility in cancer patients: Review of the literature. Int J Urol. 2010;17(4):327-31.
  9. Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL et al. Potential seminal transport of pharmaceuticals to the conceptus. Reprod Toxicol. 2015;58(0):213-21.
  10. Klemmt L, Scialli AR. The transport of chemicals in semen. Birth Defects Res B Dev Reprod Toxicol. 2005;74(2):119-31.
  11. EMA. OPDIVO. Assessment report 2015-04-23. https://goo.gl/PxOSzv
  12. Poulet FM, Wolf JJ, Herzyk DJ, DeGeorge JJ. An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors. Birth Defects Res B Dev Reprod Toxicol. 2016;107(2):108-19.
  13. Xu W, Moor RJ, Walpole ET, Atkinson VG. Pregnancy with successful foetal and maternal outcome in a melanoma patient treated with nivolumab in the first trimester: case report and review of the literature. Melanoma Res. 2019;29(3):333-337.
  14. Menzer C, Beedgen B, Rom J, Duffert CM, Volckmar AL, Sedlaczek O et al. Immunotherapy with ipilimumab plus nivolumab in a stage IV melanoma patient during pregnancy. Eur J Cancer. 2018;104:239-242.
  15. Evens AM, Brandt JS, Peer CJ, Yin T, Schaar D, Farooq F et al. Checkpoint inhibitor immunotherapy during pregnancy for relapsed-refractory Hodgkin lymphoma. Am J Hematol. 2022;97(6):833-838.
  16. Simister NE. Placental transport of immunoglobulin G. Vaccine. 2003;21(24):3365-9.