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10/4/2025

Janusmed sex and gender

Janusmed sex and gender – Diazepam

Janusmed Sex and Gender is a knowledge database providing information on sex and gender aspects of drug treatment. The knowledge database is primarily intended to be used by physicians and healthcare professionals. The texts are general and should not be considered as treatment guidelines. The individual patient’s physician is responsible for the patient’s drug treatment.

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Diazepam testing environment

Diazepam

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  1. Herr GP, Conner JT, Schehl D, Dorey F. Comparison of i m diazepam and hydroxyzine as premedicants. Br J Anaesth. 1982;54:3-9.

  2. Arbanas G, Arbanas D, Dujam K. Adverse effects of benzodiazepines in psychiatric outpatients. Psychiatr Danub. 2009;21:103-7.

  3. Neutel CI, Hirdes JP, Maxwell CJ, Patten SB. New evidence on benzodiazepine use and falls: the time factor. Age Ageing. 1996;25:273-8.

  4. Johnell K, Fastbom J. The use of benzodiazpines and related drugs amongst older people in Sweden: associated factors and concomitant use of other psychotropics. Int J Geriatr Psychiatry. 2009;24:731-8.

  5. Ochs HR, Greenblatt DJ, Divoll M, Abernethy DR, Feyerabend H, Dengler HJ. Diazepam kinetics in relation to age and sex. Pharmacology. 1981;23:24-30.

  6. Greenblatt DJ, Allen MD, Harmatz JS, Shader RI. Diazepam disposition determinants. Clin Pharmacol Ther. 1980;27:301-12.

  7. Divoll M, Greenblatt DJ, Ochs HR, Shader RI. Absolute bioavailability of oral and intramuscular diazepam: effects of age and sex. Anesth Analg. 1983;62:1-8.

  8. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.

  9. Yeates RA, Laufen H, Räder K, Leitold M. Preliminary study of the pharmacokinetics of desmethyldiazepam administered as drops or tablets. Arzneimittelforschung. 1986;36:138-40.

  10. Luk S, Atayee RS, Ma JD, Best BM. Urinary diazepam metabolite distribution in a chronic pain population. J Anal Toxicol. 2014;38:135-42.

  11. Greenblatt DJ, Harmatz JS, Shader RI. Sex differences in diazepam protein binding in patients with renal insufficiency. Pharmacology. 1978;16:26-9.

  12. Palva ES. Gender-related differences in diazepam effects on performance. Med Biol. 1985;63:92-5.

  13. Sfinx Interaktioner. Stockholm: Stockholm County Council. 2015 [cited 2015-10-05.]

  14. Routledge PA, Stargel WW, Kitchell BB, Barchowsky A, Shand DG. Sex-related differences in the plasma protein binding of lignocaine and diazepam. Br J Clin Pharmacol. 1981;11:245-50.

  15. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.

  16. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.

  17. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.

  18. Abernethy DR, Greenblatt DJ, Divoll M, Arendt R, Ochs HR, Shader RI. Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids. N Engl J Med. 1982;306:791-2.

  19. Ellinwood EH, Easler ME, Linnoila M, Molter DW, Heatherly DG, Bjornsson TD. Effects of oral contraceptives on diazepam-induced psychomotor impairment. Clin Pharmacol Ther. 1984;35:360-6.

  20. Romano-Torres M, Borja-Lascurain E, Chao-Rebolledo C, del-Río-Portilla Y, Corsi-Cabrera M. Effect of diazepam on EEG power and coherent activity: sex differences. Psychoneuroendocrinology. 2002;27:821-33.

  21. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2015 [cited 2016-04-30.]

  1. Herr GP, Conner JT, Schehl D, Dorey F. Comparison of i m diazepam and hydroxyzine as premedicants. Br J Anaesth. 1982;54:3-9.
  2. Arbanas G, Arbanas D, Dujam K. Adverse effects of benzodiazepines in psychiatric outpatients. Psychiatr Danub. 2009;21:103-7.
  3. Neutel CI, Hirdes JP, Maxwell CJ, Patten SB. New evidence on benzodiazepine use and falls: the time factor. Age Ageing. 1996;25:273-8.
  4. Johnell K, Fastbom J. The use of benzodiazpines and related drugs amongst older people in Sweden: associated factors and concomitant use of other psychotropics. Int J Geriatr Psychiatry. 2009;24:731-8.
  5. Ochs HR, Greenblatt DJ, Divoll M, Abernethy DR, Feyerabend H, Dengler HJ. Diazepam kinetics in relation to age and sex. Pharmacology. 1981;23:24-30.
  6. Greenblatt DJ, Allen MD, Harmatz JS, Shader RI. Diazepam disposition determinants. Clin Pharmacol Ther. 1980;27:301-12.
  7. Divoll M, Greenblatt DJ, Ochs HR, Shader RI. Absolute bioavailability of oral and intramuscular diazepam: effects of age and sex. Anesth Analg. 1983;62:1-8.
  8. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.
  9. Yeates RA, Laufen H, Räder K, Leitold M. Preliminary study of the pharmacokinetics of desmethyldiazepam administered as drops or tablets. Arzneimittelforschung. 1986;36:138-40.
  10. Luk S, Atayee RS, Ma JD, Best BM. Urinary diazepam metabolite distribution in a chronic pain population. J Anal Toxicol. 2014;38:135-42.
  11. Greenblatt DJ, Harmatz JS, Shader RI. Sex differences in diazepam protein binding in patients with renal insufficiency. Pharmacology. 1978;16:26-9.
  12. Palva ES. Gender-related differences in diazepam effects on performance. Med Biol. 1985;63:92-5.
  13. Sfinx Interaktioner. Stockholm: Stockholm County Council. 2015 [cited 2015-10-05.]
  14. Routledge PA, Stargel WW, Kitchell BB, Barchowsky A, Shand DG. Sex-related differences in the plasma protein binding of lignocaine and diazepam. Br J Clin Pharmacol. 1981;11:245-50.
  15. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.
  16. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.
  17. MacLeod SM, Giles HG, Bengert B, Liu FF, Sellers EM. Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol. 1979;19:15-9.
  18. Abernethy DR, Greenblatt DJ, Divoll M, Arendt R, Ochs HR, Shader RI. Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids. N Engl J Med. 1982;306:791-2.
  19. Ellinwood EH, Easler ME, Linnoila M, Molter DW, Heatherly DG, Bjornsson TD. Effects of oral contraceptives on diazepam-induced psychomotor impairment. Clin Pharmacol Ther. 1984;35:360-6.
  20. Romano-Torres M, Borja-Lascurain E, Chao-Rebolledo C, del-Río-Portilla Y, Corsi-Cabrera M. Effect of diazepam on EEG power and coherent activity: sex differences. Psychoneuroendocrinology. 2002;27:821-33.
  21. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2015 [cited 2016-04-30.]